Nefazodone hydrochloride (BMY-13754) 是一种有效的选择性 5HT2A (Ki=5.8 nM) 拮抗剂，可适度抑制 5-HT 和去甲肾上腺素的摄取（IC50 分别为 290 和 300 nM）。
| Cas No. | 82752-99-6 |
| 别名 | 萘法唑酮盐酸盐,BMY-13754; MJ-13754-1 |
| 化学名 | 1-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-3-ethyl-4-(2-phenoxyethyl)-1H-1,2,4-triazol-5(4H)-one hydrochloride |
| Canonical SMILES | ClC1=CC(N2CCN(CCCN3N=C(CC)N(CCOC4=CC=CC=C4)C3=O)CC2)=CC=C1.Cl |
| 分子式 | C25H32ClN5O2.HCl |
| 分子量 | 506.47 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at 2-8℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Nefazodone hydrochloride is an antidepressant drug. References:
[1]. Bengi Uslu, et al. Electrochemical characterisation of nefazodone hydrochloride and voltammetric determination of the drug in pharmaceuticals and human serum. Analytica Chimica ActaVolume 462, Issue 1, 26 June 2002, Pages 49–57
[2]. SHEN Wei-Yang, et al. Determination of Nefazodone Hydrochloride Tablets by HPLC. Chinese Journal of Pharmaceuticals, 2003-10 |
