MJ15 是一种有效且选择性的CB1 受体拮抗剂，对于大鼠 CB1 受体，其Ki为 27.2 pM，IC50为 118.9 pM。MJ15 在肥胖和高脂血症模型中表现出效力，可抑制饮食诱导肥胖的大鼠和小鼠的食物摄入和体重增加。
| 生物活性 | MJ15 is a potent and selectiveCB1receptorantagonist with aKiof 27.2 pM and anIC50of 118.9 pM for ratCB1receptors. MJ15 exhibits potency in obesity and hyperlipidemia models. MJ15 inhibits food intake and increases in body weight in diet-induced obese rats and mice[1]. |
| IC50& Target | rCB1-R 27.2 pM (Ki) | rCB1-R 118.9 pM (IC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
