CKLF1-C27

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CKLF1-C27

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

891861-48-6

CKLF1-C27 是 CKLF1 的 C 末端肽，与CCR4受体结合并激活ERK1/2通路。CKLF1-C27 可以通过竞争 CCR4 受体来消除 CKLF1 对细胞的影响。CKLF1-C27对促进HUVECs增殖有很大的作用。CKLF1-C27 具有用于银屑病研究的潜力。

生物活性

CKLF1-C27, a C-terminal peptide of CKLF1, binds toCCR4receptor and activatesERK1/2pathway. CKLF1-C27 can abrogate the effect of CKLF1 on cells by competing forCCR4receptor. CKLF1-C27 shows great effect on promoting proliferation on HUVECs. CKLF1-C27 has the potential for psoriasis research^[1].

IC₅₀& Target^[1]

CCR4

ERK1

ERK2

分子量

3196.78

Formula

C₁₅₁H₂₄₃N₃₉O₃₇

CAS 号

891861-48-6

Sequence Shortening

ALIYRKLLFNPSGPYQKKPVHEKKEVL

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.