Plerixafor-d4

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Plerixafor-d4

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1246819-87-3

包装与价格：

包装	价格(元)
1mg	询价
5mg	询价

普乐沙福 d4

Plerixafor-d4 是 Plerixafor 的氘代物。Plerixafor (AMD 3100) 是选择性的CXCR4拮抗剂，IC₅₀为 44 nM。Plerixafor 是一种免疫刺激剂和造血干细胞动员剂，也是 CXCR7 的变构激动剂。Plerixafor 抑制HIV-1和HIV-2的复制，EC₅₀为 1-10 nM。

生物活性	Plerixafor-d4 is the deuterium labeled Plerixafor. Plerixafor (AMD 3100) is a selectiveCXCR4antagonist with anIC₅₀of 44 nM. Plerixafor, an immunostimulant and ahematopoietic stem cell (HSC)mobilizer, is an allosteric agonist ofCXCR7. Plerixafor inhibitsHIV-1andHIV-2replication with anEC₅₀of 1-10 nM^[1]^[2]^[3]^[4]^[7].
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].
分子量	506.81
Formula	C₂₈H₅₀D₄N₈
CAS 号	1246819-87-3
中文名称	普乐沙福 d4
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.