NoxaBH3 是一种基于半胱氨酸的交联肽，具有增加的细胞渗透性和对 Mcl-1 的更高抑制活性。NoxaBH3 与CXCR4的内源性配体结合，产生泛素-NoxaBH3偶联物。随后 NoxaBH3 被输送到癌症细胞。
| 生物活性 | NoxaBH3 is a cysteine-based cross-linked peptide with increased cell permeability and higher inhibitory activity againstMcl-1. NoxaBH3 binds to the endogenousCXCR4ligand to produce ubiquitin-Noxabh3 conjugate. NoxaBH3 is then delivered tocancercells[1]. |
| 分子量 | |
| Formula | |
| Sequence | Ala-Ala-Cys-Leu-Arg-Arg-Ile-Gly-Asp-Cys-Val-Asn-Leu-Arg-Gln-Lys-Leu-Leu-Asn |
| Sequence Shortening | |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
