(±)-AMG 487 是 AMG 487 的外消旋体。AMG 487 是一种有效的，具有口服活性的选择性趋化因子受体3 (CXCR3) 拮抗剂，抑制 CXCL10 和 CXCL11 与 CXCR3 结合的IC50值分别为 8.0 和 8.2 nM。
| 生物活性 | (±)-AMG 487 is a racemate of AMG 487. AMG 487 is an orally active and selective antagonist ofCXC chemokine receptor3(CXCR3)which inhibits the binding of CXCL10 and CXCL11 toCXCR3withIC50s of 8.0 and 8.2 nM, respectively[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
