HF50731 (化合物 21) 是一种有效的CXCR4拮抗剂。HF50731 具有较强的CXCR4结合亲和力，IC50为 19.8 nM。HF50731 通过 CXCR4 共受体有效抑制钙动员、细胞迁移和HIV-1感染，IC50值分别为 119.2 nM、621.4 nM 和 1.5 μM。
| 生物活性 | HF50731 (compound 21) is a potentCXCR4antagonist. HF50731 shows strongCXCR4binding affinity, withIC50of 19.8 nM. HF50731 effectively inhibits calcium mobilization, cell migration, andHIV-1infectionviaCXCR4coreceptor, withIC50values of 119.2 nM, 621.4 nM and 1.5 μM[1]. |
| IC50& Target | HIV-1 1.5 μM (IC50) | CXCR4 19.8 nM (IC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
