CAS NO: | 2580154-02-3 |
生物活性 | Certepetide (CEND-1) is a bifunctional cyclic peptide (a.k.a. iRGD). Certepetide is a tumor-penetrating enhancer via RGD motif interaction withalphav-integrinsand via activatingNRP-1, and transforms the solid tumor microenvironment into a temporary drug conduit. Certepetide accumulates in tumors, and is used in the research of pancreaticcancerand other solid tumors[1][2][3]. |
IC50& Target | Alphav-integrins, NRP-1[3]. |
Clinical Trial | |
分子量 | 989.09 |
Formula | C37H60N14O14S2 |
CAS 号 | 2580154-02-3 |
Sequence Shortening | Ac-CRGDKGPDC-NH2 (Disulfide bridge: Cys1-Cys9) |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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