Anti-inflammatory agent 20 (化合物 5a) 是一种有效的NO活性抑制剂。Anti-inflammatory agent 20 具有抗炎活性。Anti-inflammatory agent 20 通过抑制NF-κB和MAPK信号的激活从而降低 IL-6、TNF-α、iNOS 和 COX-2 的上调来抑制 LPS 诱导的炎症反应。
生物活性 | Anti-inflammatory agent 20 (compound 5a) is a potent inhibitor ofNOactivity. Anti-inflammatory agent 20 shows anti-inflammatory activity. Anti-inflammatory agent 20 suppresses LPS-induced inflammation via inhibiting the activation ofNF-κBandMAPKsignaling and thereby reducingIL-6, TNF-α,iNOS, andCOX-2upregulation[1]. |
IC50& Target | |
分子量 | |
Formula | |
CAS 号 | |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |