COX-2-IN-14 (化合物 2a) 是一种强效且选择性的COX-2(环氧化酶 -2) 抑制剂。COX-2-IN-14 在 COX-2 共晶体的活性位点上有效结合。COX-2-IN-14 在体内表现出高水平的的抗炎活性,降低小鼠耳朵水肿和髓过氧化物酶 (MPO) 活性。
生物活性 | COX-2-IN-14 (compound 2a) is a potent and selectiveCOX-2(cyclooxygenase-2) inhibitor. COX-2-IN-14 shows effective binding at the active site ofCOX-2co-crystal. COX-2-IN-14 exhibits a high level ofin vivoanti-inflammatory activity, reducing ear edema and myeloperoxidase (MPO) activity in mice[1]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |