Hamaudol

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Hamaudol

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

735-46-6

Hamaudol 是从Saposhnikovia divaricata中分离出的一种色酮。Hamaudol 对环加氧酶(COX)-1和COX-2的活性具有明显的抑制能力，其IC₅₀值分别为 0.30、0.57 mM，并且具有有效抗炎作用，可用于缓解疼痛的研究。

生物活性

Hamaudol is a chromone isolated fromSaposhnikovia divaricata. Hamaudol shows significant inhibitory activity oncyclooxygenase (COX)-1andCOX-2activities withIC₅₀values of 0.30, 0.57 mM, respectively, and has potent analgesia and anti-inflammary effects^[1]^[2].

IC₅₀& Target

COX-1

0.3 mM (IC₅₀)

COX-2

0.57 mM (IC₅₀)

体内研究
(In Vivo)

Hamaudol (Compound 7) increases the potency to exhibit a potent analgesia at doses of 1, 5 and 10 mg/kg in mice, although it do not show clear dose dependency^[1].

分子量

276.28

Formula

C₁₅H₁₆O₅

CAS 号

735-46-6

结构分类

Phenols
Monophenols

Ketones, Aldehydes, Acids

来源

Plants
Umbelliferae
Saposhnikovia divaricata(Turcz.) Schischk.

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.