COX-2-IN-22 (Compound 4h) 是一种COX-2抑制剂，IC50为 8.6 μM。COX-2-IN-22 也抑制AChE、BChE、β-Secretase、LOX-5和DPPH，IC50值分别为 2.8、6.3,、15.3、 13.9 和 6.8 μM。COX-2-IN-22 能通过血脑屏障。
| 生物活性 | COX-2-IN-22 (Compound 4h) is aCOX-2inhibitor with anIC50of 8.6 μM. COX-2-IN-22 also inhibitsAChE,BChE,β-Secretase,LOX-5andDPPHwithIC50values of 2.8, 6.3, 15.3, 13.9 and 6.8 μM, respectively. COX-2-IN-22 can cross BBB[1]. |
| IC50& Target | COX-2 8.6 μM (IC50) | AChE 2.8 μM (IC50) | BChE 6.3 μM (IC50) | β-Secretase 15.3 μM (IC50) | LOX-5 13.9 μM (IC50) | DPPH 6.8 μM (IC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
