OP-3633 is a potent and selective steroidalglucocorticoid receptor(GR)antagonist with anIC₅₀of 29 nM, with inhibition of GR transcriptional activity. OP-3633 exhibits lowprogesterone receptor(PR) agonism andandrogen receptor(AR) antagonism^[1].

IC50: 29 nM (GR)^[1]

OP-3633 exhibits low progesterone receptor (PR) agonism with an EC₅₀higher than 2500 nM^[1].
OP-3633 exhibits low androgen receptor (PR) antagonism, with an IC₅₀of 1135 nM^[1].

445.64

C₃₀H₃₉NO₂

2102494-14-2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.