Secukinumab

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Secukinumab

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1229022-83-6

司库奇尤单抗
AIN457

Secukinumab (AIN457) 是一种针对白细胞介素(IL-17A)的高亲和力单克隆抗体。Secukinumab (AIN457) 是首创的抗 IL-17 剂，用于研究斑块状银屑病、强直性脊柱炎和银屑病关节炎。

生物活性

Secukinumab (AIN457) is a high affinity, human monoclonal antibody targeted againstinterleukin (IL)-17A. Secukinumab is the first-in-class anti-IL-17 agent used for the research of plaque psoriasis, ankylosing spondylitis and psoriatic arthritis^[1]^[2].

IC₅₀& Target^[1]

IL-17A

体外研究
(In Vitro)

Secukinumab is a fully human monoclonal antibody that selectively binds to and neutralizes interleukin-17A^[2].
Secukinumab (1 nM, 10 nM, and 100 nM) inhibits IL17A and IL17A/TNF a-induced increase in protein levels of IL6 in human astrocytes^[3].

Clinical Trial

性状

Liquid

CAS 号

1229022-83-6

中文名称

苏金单抗；司库奇尤单抗

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.