EGFR-IN-27

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EGFR-IN-27

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2752328-62-2

EGFR-IN-27 是一种有效的EGFR抑制剂，对 EGFR Del, L858R, Del/T790M, L858R/T790M, Del/T790M/C797S, L858R/T790M/C797S 的IC₅₀为<50 nM。

生物活性

EGFR-IN-27 is a potentEGFRinhibitor withIC₅₀s of<50 nm forEGFRDel, L858R, Del/T790M, L858R/T790M, Del/T790M/C797S, and L858R/T790M/C797S, respectively (WO2021249324A1, compound 511)^[1].

IC₅₀& Target^[1]

EGFR^del19

<50 nM (IC₅₀)

EGFR^L858R

<50 nM (IC₅₀)

EGFR^L858R/T790M

<50 nM (IC₅₀)

EGFR^{del19 T790M C797S}

<50 nM (IC₅₀)

EGFR (C797S/T790M/L858R)

<50 nM (IC₅₀)

EGFR^{del19 T790M}

<50 nM (IC₅₀)

分子量

655.77

Formula

C₃₅H₄₆N₉O₂P

CAS 号

2752328-62-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.