EGFR/BRAF-IN-1 (compound 21) 是一种 2,3-dihydropyrazino[1,2-a]indole-1,4-dione 衍生物，一种有效的EGFR/BRAF抑制剂，对 BRAFV600E的IC50为 45 nM。EGFR/BRAF-IN-1 抑制癌细胞增殖 (GI50=35 nM)。EGFR/BRAF-IN-1 显示出良好的抗氧化活性。
| 生物活性 | EGFR/BRAF-IN-1 (compound 21), a 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivative, is a potentEGFR/BRAFinhibitor with anIC50of 45 nM forBRAFV600E. EGFR/BRAF-IN-1 inhibitscancercell proliferation (GI50=35 nM). EGFR/BRAF-IN-1 shows good antioxidant activity[1]. |
| IC50& Target[1] | EGFR | BRafV600E 45 nM (IC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
