EGFR-IN-52 (Compound 4) 是一种有效的EGFR抑制剂，对EGFR 、EGFR L858R-TK和EGFR T790M-TK的IC50值分别为 0.358、86.02 和 432.67 μM。EGFR-IN-52 对癌细胞具有毒性，诱导细胞凋亡 (apoptosis)。
| 生物活性 | EGFR-IN-52 (Compound 4) is a potentEGFRinhibitor withIC50values of 0.358, 86.02 and 432.67 μM againstEGFR,EGFRL858R-TKandEGFRT790M-TK, respectively. EGFR-IN-52 shows cytotoxic activity againstcancercell lines and inducesapoptosis[1]. |
| IC50& Target | EGFR 0.358 μM (IC50) | EGFRL858R 86.02 μM (IC50) | EGFRT790M 432.67 μM (IC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
