EGFR-IN-55 (Compound 8a) 是一种有效的EGFR抑制剂，对EGFRWT和EGFRL858R/T790M的IC50值分别为 70 nM 和 3.9 nM。EGFR-IN-55 阻滞 NCI-H1975 细胞 G0/G1 期，具有抗癌活性。
| 生物活性 | EGFR-IN-55 (Compound 8a) is a potentEGFRinhibitor withIC50values of 70 nM and 3.9 nM againstEGFRWTandEGFRL858R/T790M, respectively. EGFR-IN-55 arrests NCI-H1975 cells in G0/G1 phase and shows anticancer activity[1]. |
| IC50& Target | EGFRL858R/T790M 3.9 nM (IC50) | EGFRWT 70 nM (IC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
