HER2-IN-12

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HER2-IN-12

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

HER2-IN-12 是一种HER2抑制剂 (IC₅₀: 121 nM)。HER2-IN-12 可用于癌症研究，如乳腺癌。

生物活性

HER2-IN-12 is aHER2inhibitor (IC₅₀: 121 nM). HER2-IN-12 can be used in the research of cancers, such as breastcancer^[1].

IC₅₀& Target^[1]

HER2

121 nM (IC₅₀)

体外研究
(In Vitro)

HER2-IN-12 (Compound 44, 72 h) exhibits broad cytotoxicity against series of cancer cells (HepG2, MCF-7, HCT116, PC3, HeLa)^[1].

Cell Viability Assay^[1]

Cell Line:	HepG2, MCF-7, HCT116, PC3, HeLa
Concentration:	0-100 μM approximately
Incubation Time:	72 h
Result:	Inhibited cancer cell viability with IC₅₀values ranging from 3.65 μM (HeLa) to 21.89 μM (PC3).

分子量

436.33

Formula

C₁₇H₁₈BrN₅O₂S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.