LP117是一种新型且有效的5-脂氧合酶(5-LO)产品合成抑制剂,其IC50值为1.1μM。
Cas No. | 1056468-55-3 |
Canonical SMILES | CCCCC(SC1=NC(NC2=CC=C3N=CC=CC3=C2)=CC(Cl)=N1)C(OCC)=O |
分子式 | C21H23ClN4O2S |
分子量 | 430.95 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | LP117 is a novel and potent inhibitor of 5-Lipoxygenase (5-LO) product synthesis with an IC50 of 1.1 μM. [1]. Werz O, et al. Novel and potent inhibitors of 5-lipoxygenase product synthesis based on the structure of pirinixic acid. J Med Chem. 2008 Sep 11;51(17):5449-53. |