(Z)-GW 5074 是一种化合物，可以与突变型亨廷顿蛋白 (mHTT) 和LC3相互作用，但对野生型 HTT 无作用。(Z)-GW 5074 可抑制c-Raf的活性，不影响自噬，在神经退行性疾病中有效。
| 生物活性 | (Z)-GW 5074 is a compound which interacts with bothmHTT (mutanthuntingtinprotein)andLC3, but not but not with the wild-type HTT protein. (Z)-GW 5074 inhibitsc-Raf, shows no effect onautophagy, and is effective for neurodegenerative disorder[1]. |
| IC50& Target[1] | |
| 分子量 | |
| Formula | |
| CAS 号 | |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
