Ezatiostat

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Ezatiostat

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:	168682-53-9
规格:	≥98%

包装与价格：

理化性质和储存条件

	Name: Ezatiostat CAS#: 168682-53-9 (free base) Chemical Formula: C27H35N3O6S Exact Mass: 529.22466 Molecular Weight: 529.6483 Elemental Analysis: C, 61.23; H, 6.66; N, 7.93; O, 18.12; S, 6.05
Storage	-20℃ for 3 years in powder form
Storage	-80℃ for 2 years in solvent
Technical Information	Synonym: TLK199; TLK-199; TLK 199; Ezatiostat; TER-199; TLK-199 hydrochloride; TER 199; TLK 199 hydrochloride; TER199; TLK199 hydrochloride; trade name: Telintra Chemical Name: (S)-ethyl 2-amino-5-(((R)-3-(benzylthio)-1-(((S)-2-ethoxy-2-oxo-1-phenylethyl)amino)-1-oxopropan-2-yl)amino)-5-oxopentanoate InChi Key: GWEJFLVSOGNLSS-FIXSFTCYSA-N InChi Code: InChI=1S/C27H35N3O6S/c1-3-35-26(33)21(28)15-16-23(31)29-22(18-37-17-19-11-7-5-8-12-19)25(32)30-24(27(34)36-4-2)20-13-9-6-10-14-20/h5-14,21-22,24H,3-4,15-18,28H2,1-2H3,(H,29,31)(H,30,32)/t21-,22-,24-/m0/s1 SMILES Code: O=C(OCC)[C@@H](N)CCC(N[C@@H](CSCC1=CC=CC=C1)C(N[C@@H](C2=CC=CC=C2)C(OCC)=O)=O)=O

实验参考方法

Patients who responded to ezatiostat under-expressed miR-129 (A) and over-expressed miR-155 (B). J Hematol Oncol. 2012 May 6;5:20.	Three pathways, mTOR, JAK2, and JNK, were under-expressed in patients who responded to ezatiostat. J Hematol Oncol. 2012 May 6;5:20.

Patients who responded to ezatiostat under-expressed miR-129 (A) and over-expressed miR-155 (B). J Hematol Oncol. 2012 May 6;5:20.

Three pathways, mTOR, JAK2, and JNK, were under-expressed in patients who responded to ezatiostat. J Hematol Oncol. 2012 May 6;5:20.