B-Raf IN 9

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B-Raf IN 9

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2477725-18-9

B-Raf IN 9 (compound 8b) 是一种有效的B-Raf抑制剂，其IC₅₀为 24.79 nM。B-Raf IN 9 诱导凋亡，细胞周期阻滞于 G2/M 期。B-Raf IN 9 对人前列腺癌 PC-3 细胞表现出较强的抗肿瘤活性，IC₅₀值为 7.83 μM。

生物活性

B-Raf IN 9 (compound 8b) is a potentB-Rafinhibitor, with anIC₅₀of 24.79 nM. B-Raf IN 9 inducesapoptosisand shows cell cycle arrest at G2/M phase. B-Raf IN 9 exhibits potent antitumor activity against human prostatecancerPC-3 cell line, with anIC₅₀of 7.83 μM^[1].

IC₅₀& Target

B-Raf

24.97 ± 0. nM (IC₅₀)

分子量

400.50

Formula

C₂₃H₂₀N₄OS

CAS 号

2477725-18-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.