B-Raf IN 7

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B-Raf IN 7

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CAS NO:

2477725-07-6

B-Raf IN 7 (compound 6a) 是一种有效的B-Raf抑制剂，其IC₅₀为 110.23 nM。B-Raf IN 7 对结肠癌 (HCT-116)、乳腺癌 (MCF-7)、肝细胞癌 (HEPG-2)、人宫颈癌 (Hela) 和人前列腺癌 (PC-3) 细胞表现出较强的抗肿瘤活性，IC₅₀值分别为 7.50、9.87、10.57、11.63 和 12.83 μM。

生物活性

B-Raf IN 7 (compound 6a) is a potentB-Rafinhibitor, with anIC₅₀of 110.23 nM. B-Raf IN 7 exhibits antitumor activity against colon carcinoma (HCT-116), mammary gland (MCF-7), hepatocellular carcinoma (HEPG-2), human cervical carcinoma (Hela) and human prostatecancer(PC-3) cells, withIC₅₀values of 7.50, 9.87, 10.57, 11.63 and 12.83 μM^[1].

IC₅₀& Target

B-Raf

110.23 ± 0 nM (IC₅₀)

分子量

328.33

Formula

C₁₅H₁₆N₆O₃

CAS 号

2477725-07-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.