Urocortin III(mouse)(free acid)

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Urocortin III (mouse) (free acid) 是一种选择性的CRF2受体激动剂 (对CRF2受体具有高亲和力)。Urocortin III (mouse) (free acid) 可显著抑制胃排空而不改变结肠运输。

生物活性

Urocortin III (mouse) (free acid) is a selectiveCRF2 receptoragonist (with high affinity for theCRF2receptor). Urocortin III (mouse) (free acid) significantly inhibits gastric emptying without modifying colonic transit^[1]^[2].

IC₅₀& Target

CRF2 receptor^[1]^[2].

体内研究
(In Vivo)

Urocortin III (mouse) (free acid) (120 μg/kg; i.p.; single) inhibits gastric emptying of a solid meal without modifying colonic transit in mice^[1].

Animal Model:	Adult male C57BL/6 mice (6 to 8-week-old)^[1].
Dosage:	12, 60, 120 μg/kg
Administration:	Intraperitoneal injection; single
Result:	Inhibited gastric emptying of the solid meal only at the highest dose, and did not alter distal colonic transit.

分子量

4171.26

Formula

C₁₈₆H₃₁₁N₅₁S₂

Sequence Shortening

FTLSLDVPTNIMNILFNIDKAKNLRAKAAANAQLMAQI

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.