Baloxavir (Baloxavir acid) 源自前药 Baloxavir marboxil,是 A 型和 B 型流感病毒聚合酶 PA 亚基内的一流、有效和选择性的帽依赖性核酸内切酶 (CEN) 抑制剂。
Cas No. | 1985605-59-1 |
别名 | 巴洛沙韦,Baloxavir acid; S-033447 |
Canonical SMILES | O=C1N2[C@](COCC2)([H])N([C@@H]3C4=CC=CC=C4SCC5=C(F)C(F)=CC=C35)N6C1=C(O)C(C=C6)=O |
分子式 | C24H19F2N3O4S |
分子量 | 483.49 |
溶解度 | DMSO : ≥ 50 mg/mL (87.48 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Baloxavir is an anti-influenza agent extracted from patent WO 2017104691 A1. References: [1]. Shishido Takao, et al. Medicine for treating influenza characterized by comprising combination of cap-dependent endonuclease inhibitor with anti-influenza drug. WO 2017104691 A1. |