Palitantin ((±)-Palitantin) 是常青菌对巴西利什曼原虫的代谢产物,对巴西利什曼原虫具有抗原生动物作用。
Cas No. | 15265-28-8 |
别名 | 徘徊青霉素,(±)-Palitantin |
化学名 | (2R,3S,5R,6R)-rel-3-(1E,3E)-1,3-heptadien-1-yl-5,6-dihydroxy-2-(hydroxymethyl)-cyclohexanone |
Canonical SMILES | O=C1[C@H](O)[C@H](O)C[C@@H](/C=C/C=C/CCC)[C@@H]1CO |
分子式 | C14H22O4 |
分子量 | 254.3 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Palitantin is a fungal metabolite originally isolated from P. palitans. It inhibits HIV-1 integrase with IC50 values of 350 and 268 uM for 3'-processing and strand transfer activity, respectively. Palitantin has been used as a standard for dereplication of natural products. |