Bucindolol是一种β1-肾上腺素能受体阻滞剂，具有内在拟交感活性，用于心力衰竭的研究。
| Cas No. | 71119-11-4 |
| 别名 | 布新洛尔 |
| 化学名 | (S)-2-(3-((1-(1H-indol-3-yl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)benzonitrile |
| Canonical SMILES | O[C@H](COC1=CC=CC=C1C#N)CNC(C)(C)CC2=CNC3=CC=CC=C23 |
| 分子式 | C22H25N3O2 |
| 分子量 | 363.45 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 20 mg/ml,Ethanol: 500 µ g/ml |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Bucindolol is a β1-adrenergic receptor blocker, with intrinsic sympathomimetic activity, used in the research of heart failure[1]. References:
[1]. Liggett SB, et al. A polymorphism within a conserved beta(1)-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure. Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11288-93. |
