SEW2871 是一种具有口服活性、强效、高选择性的 S1P1（1 型鞘氨醇受体）激动剂，EC50 为 13.8 nM。
| Cas No. | 256414-75-2 |
| 别名 | 5-[4-苯基-5-(三氟甲基)-2-噻吩基]-3-[3-(三氟甲基)苯基]-1,2,4-恶二唑 |
| 化学名 | 5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-3-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole |
| Canonical SMILES | FC(F)(C1=C(C2=CC=CC=C2)C=C(C3=NC(C4=CC=CC(C(F)(F)F)=C4)=NO3)S1)F |
| 分子式 | C20H10F6N2OS |
| 分子量 | 440.36 |
| 溶解度 | ≥ 22.05mg/mL in DMSO with ultrasonic and warming, ≥ 22mg/mL in EtOH with ultrasonic |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
