hCAII-IN-9

立即咨询

hCAII-IN-9

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

hCAII-IN-9 是一种强效的碳酸酐酶抑制剂，IC₅₀分别为 1.18 μM (hCA II), 0.17 μM (hCA IX), and 2.99 μM (hCA XII)。hCAII-IN-9 没有血脑屏障透过性。

生物活性

hCAII-IN-9 is a potentcarbonic anhydrase inhibitor withIC₅₀s of 1.18 μM (hCA II), 0.17 μM (hCA IX), and 2.99 μM (hCA XII), respectively. hCAII-IN-9 has no blood-brain barrier permeability^[1].

IC₅₀& Target^[1]

hCA II

1.18 μM (IC₅₀)

hCA IX

0.17 μM (IC₅₀)

hCA XII

2.99 μM (IC₅₀)

体外研究
(In Vitro)

hCAII-IN-9 (compound 11) (100 μM; 24-48 h) inhibits BHK-21 and HEK-293 cells with cell viability rates of 48% and 72%^[1].

体内研究
(In Vivo)

hCAII-IN-9 (compound 11) has no blood-brain barrier permeability^[1].

分子量

417.89

Formula

C₁₅H₁₆ClN₃O₅S₂

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.