BOT-64 是一种inhibitory κB (IκB) kinase β (IKKβ)抑制剂，IC50为 1 μM。BOT-64 阻断脂多糖诱导的 NF-κb 的激活和 NF-κB 调控的炎症基因转录。
| 生物活性 | BOT-64 is aninhibitory κB (IκB) kinase β (IKKβ)inhibitor with anIC50of 1 μM. BOT-64 blocks lipopolysaccharide-induced nuclear factor-κB activation and nuclear factor-κB-regulated inflammatory gene transcription[1]. |
| IC50& Target | |
体内研究
(In Vivo) | BOT-64 (3-30 mg/kg) increases the survival rates of endotoxin LPS-shocked mice[1].
|
| 分子量 | |
| Formula | |
| CAS 号 | |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
