eap1-Nrf2-IN-12 是一种有效的Keap1-Nrf2抑制剂,IC50值为 2.30 μM。Keap1-Nrf2-IN-12 在人肝微粒体中表现出代谢稳定性。
生物活性 | Keap1-Nrf2-IN-12 is a potentKeap1-Nrf2inhibitor with anIC50value of 2.30 μM. Keap1-Nrf2-IN-12 shows metabolic stability in human liver microsomes[1]. |
IC50& Target | IC50: 2.30 μM (Keap1-Nrf2)[1]. |
体外研究 (In Vitro) | Keap1-Nrf2-IN-12 (compound 9a) shows metabolic stability in human liver microsomes with slight changes (97.7% remained) after 90 min of incubation[1].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |