Sonlicromanol

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Sonlicromanol

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1541170-75-5

KH176

Sonlicromanol (KH176) 是具有口服活性的活性氧(ROS)的调节剂。可用于线粒体疾病的研究。

生物活性

Sonlicromanol (KH176) is an orally activereactive oxygen species(ROS)modulator for the study in mitochondrial disease^[1]^[2].

体内研究
(In Vivo)

Sonlicromanol (KH176, 10 mg/kg, ip, twice daily) has promising, but independent and nonadditive, properties for the pharmacological treatment of CI-deficiency-related mitochondrial diseases^[3].

Animal Model:	Ndufs4^–/–mice^[3].
Dosage:	10 mg/kg.
Administration:	Twice daily by intraperitoneal injection.
Result:	Increased lifespan of Ndufs4^–/–mice similar as KH176 and Clofibrate single treatment.

Clinical Trial

分子量

332.44

Formula

C₁₉H₂₈N₂O₃

CAS 号

1541170-75-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.