AKT-IN-13

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AKT-IN-13

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2459489-51-9

AKT-IN-13 (compound 4b) 是一种有效的Akt抑制剂，对 Akt1、Akt2 和 Akt3 的IC₅₀分别为 1.6 nM、2.4 nM 和 0.3 nM。AKT-IN-13 可用于抗癌研究。

生物活性

AKT-IN-13 (compound 4b) is a potentAktinhibitor withIC₅₀s of 1.6 nM, 2.4 nM and 0.3 nM forAkt1,Akt2andAkt3, respectively. AKT-IN-13 can be used for researching anticancer^[1].

IC₅₀& Target^[1]

Akt1

1.6 nM (IC₅₀)

Akt2

2.4 nM (IC₅₀)

Akt3

0.3 nM (IC₅₀)

体外研究
(In Vitro)

AKT-IN-13 (compound 4b) displays good potency in the LNCap cell line with an IC₅₀value of 103 nM and a high free fraction with 51.3% human plasma protein binding (PPB)^[1].

分子量

470.99

Formula

C₂₄H₃₁ClN₆O₂

CAS 号

2459489-51-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.