| CAS NO: | 60940-34-3 |
| 规格: | ≥98% |
| 包装 | 价格(元) |
| 10mg | 询价 |
| 25mg | 询价 |
| 50mg | 询价 |
| 100mg | 询价 |
| 250mg | 询价 |
| 500mg | 询价 |
| 1g | 询价 |
| Molecular Weight (MW) | 274.18 |
|---|---|
| Formula | C13H9NOSe |
| CAS No. | 60940-34-3 |
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent | |
| Solubility (In vitro) | DMSO:10 mM |
| Water: <1 mg/mL | |
| Ethanol: <1 mg/mL | |
| SMILES Code | O=C1N(C2=CC=CC=C2)[Se]C3=CC=CC=C13 |
| Synonyms | SPI-1005; PZ-51; DR3305; CCG 39161; SPI1005; PZ51; DR 3305; CCG39161; SPI 1005; PZ 51; DR-3305; CCG-39161 |
| In Vitro | In vitro activity: Ebselen is a small-molecule capsid Inhibitor of HIV-1 replication. Ebselen is an organoselenium compound, as an inhibitor of HIV-1 capsid CTD dimerization. Ebselen inhibits early viral postentry events of the HIV-1 life cycle by impairing the incoming capsid uncoating process. Ebselen is a non-toxic seleno-organic drug with anti-inflammatory and antioxidant properties. Ebselen is an inhibitor of inositol monophosphatase (IMPase). Ebselen permeates the blood-brain barrier and inhibits endogenous inositol monophosphatase in mouse brain. Kinase Assay: Ebselen is a non-toxic seleno-organic drug with anti-inflammatory and antioxidant properties. Ebselen is an inhibitor of inositol monophosphatase (IMPase). |
|---|---|
| In Vivo | Ebselen permeates the blood-brain barrier and inhibits endogenous inositol monophosphatase in mouse brain. |
| Animal model | Mouse |
| Formulation & Dosage | N/A |
| References | Antimicrob Agents Chemother. 2016 Mar 25;60(4):2195-208. |
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