PI3K-IN-6 (compound 20a) 是具有口服有效的、高度选择性的磷脂酰肌醇三激酶(PI3K) β/δ的抑制剂，其对 PI3K β/δ 的IC50值分别为 7.8 nM 和 5.3 nM。PI3K-IN-6 (compound 20a) 可用于磷酸酶和紧张素同系物 (PTEN) 缺乏性肿瘤的研究。
| 生物活性 | PI3K-IN-6 (compound 20a) is an oral active and highly selectivephosphoinositide 3-kinase (PI3K) β/δinhibitor, withIC50values of 7.8 nM/5.3 nM forPI3Kβ/δ, respectively. PI3K-IN-6 (compound 20a) has potential top treatphosphataseand tensin homolog (PTEN) feficient tumors[1]. |
| IC50& Target | PI3Kβ 7.8 nM (IC50) | PI3Kδ 5.3 nM (IC50) | PI3Kα 850 nM (IC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
