Thalidomide-NH-C6-NH2 是一种合成的E3 连接酶配体 -linker 偶联物,包含基于 Thalidomide 的 cereblon 配体和 1 个 linker。
生物活性 | Thalidomide-NH-C6-NH2 is a synthesizedE3 ligase ligand-linker conjugatethat incorporates the Thalidomide basedcereblonligand and a linker used inPROTACtechnology[1]. |
体外研究 (In Vitro) | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |