CAS NO: | 1835705-74-2 |
生物活性 | Pomalidomide-PEG6-butyl iodide is a synthesizedE3 ligase ligand-linker conjugatethat incorporates the Pomalidomide basedcereblonligand and 6-unit PEG linker used inPROTACtechnology[1]. | ||||||||||||||||
IC50& Target |
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体外研究 (In Vitro) | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | ||||||||||||||||
分子量 | 761.60 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C31H44IN3O11 | ||||||||||||||||
CAS 号 | 1835705-74-2 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 100 mg/mL(131.30 mM;Need ultrasonic) 配制储备液
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