(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) hydrochloride 是一种合成的 E3 连接酶配体-linker 偶联物 (E3 ligase ligand-linker conjugate，包含基于 VH032 的 VHL 配体和 1 个 linker，可用于合成 PROTAC 分子。
| 生物活性 | (S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology[1]. |
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体外研究
(In Vitro) | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | 4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
