Pomalidomide-PEG6-NH2 hydrochloride是一种合成的 E3 连接酶配体-linker 偶联物,包含基于 Pomalidomide 的 cereblon 配体和 6 个单元的 PEG linker,应用于 PROTAC 技术。
生物活性 | Pomalidomide-PEG6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide basedcereblonligand and 6-unit PEG linker used inPROTACtechnology. |
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体外研究 (In Vitro) | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |