Pomalidomide 4'-PEG3-azide 是一个合成的 E3 连接酶配体-linker 偶联物，包含基于 Pomalidomide 的 cereblon 配体和 1 个 linker，可用于 iRucaparib-TP3 的合成。iRucaparib-TP3 是一种基于 Rucaparib 使用 PROTAC 方法的高效 PARP1 降解剂。
| 生物活性 | Pomalidomide 4'-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-basedcereblonligand and a linker. Pomalidomide 4'-PEG3-azide can be used for the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3 is a highly efficientPARP1 degrader based on Rucaparib by using thePROTACapproach[1]. |
| IC50& Target[1] | |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
