Thalidomide-NH-C4-NH2 TFA (compound 29c) 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 Thalidomide 的 cereblon 配体和 linker，用于合成PROTAC BRD2/BRD4 degrader-1 (HY-130612)。PROTAC-BRD2/BRD4 降解剂-1是一种高效、选择性的 BET 蛋白 BRD4 和 BRD2 降解剂。
| 生物活性 | Thalidomide-NH-C4-NH2 TFA (compound 29c) is an E3 ligase ligand-linker conjugate, and incorporates the Thalidomide basedcereblonligand and a linker. Thalidomide-NH-C4-NH2 TFA is used inPROTACBRD2/BRD4 degrader-1 (HY-130612).PROTACBRD2/BRD4 degrader-1 is a potent and selective BET proteinBRD4andBRD2degrader[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
