ID   ACYP_THEKO              Reviewed;          91 AA.
AC   Q5JDG7;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Acylphosphatase;
DE            EC=3.6.1.7;
DE   AltName: Full=Acylphosphate phosphohydrolase;
GN   Name=acyP; OrderedLocusNames=TK2031;
OS   Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS   (Pyrococcus kodakaraensis (strain KOD1)).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=69014;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-918 / JCM 12380 / KOD1;
RX   PubMed=15710748; DOI=10.1101/gr.3003105;
RA   Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT   "Complete genome sequence of the hyperthermophilic archaeon Thermococcus
RT   kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
RL   Genome Res. 15:352-363(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=an acyl phosphate + H2O = a carboxylate + H(+) + phosphate;
CC         Xref=Rhea:RHEA:14965, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:29067, ChEBI:CHEBI:43474, ChEBI:CHEBI:59918; EC=3.6.1.7;
CC   -!- SIMILARITY: Belongs to the acylphosphatase family. {ECO:0000305}.
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DR   EMBL; AP006878; BAD86220.1; -; Genomic_DNA.
DR   RefSeq; WP_011250981.1; NC_006624.1.
DR   AlphaFoldDB; Q5JDG7; -.
DR   SMR; Q5JDG7; -.
DR   STRING; 69014.TK2031; -.
DR   EnsemblBacteria; BAD86220; BAD86220; TK2031.
DR   GeneID; 3235065; -.
DR   KEGG; tko:TK2031; -.
DR   PATRIC; fig|69014.16.peg.1985; -.
DR   eggNOG; arCOG01674; Archaea.
DR   HOGENOM; CLU_141932_3_2_2; -.
DR   InParanoid; Q5JDG7; -.
DR   OMA; VGFRWSM; -.
DR   OrthoDB; 111329at2157; -.
DR   PhylomeDB; Q5JDG7; -.
DR   Proteomes; UP000000536; Chromosome.
DR   GO; GO:0003998; F:acylphosphatase activity; IBA:GO_Central.
DR   InterPro; IPR020456; Acylphosphatase.
DR   InterPro; IPR001792; Acylphosphatase-like_dom.
DR   InterPro; IPR036046; Acylphosphatase-like_dom_sf.
DR   InterPro; IPR017968; Acylphosphatase_CS.
DR   PANTHER; PTHR47268; PTHR47268; 1.
DR   Pfam; PF00708; Acylphosphatase; 1.
DR   PRINTS; PR00112; ACYLPHPHTASE.
DR   SUPFAM; SSF54975; SSF54975; 1.
DR   PROSITE; PS00150; ACYLPHOSPHATASE_1; 1.
DR   PROSITE; PS00151; ACYLPHOSPHATASE_2; 1.
DR   PROSITE; PS51160; ACYLPHOSPHATASE_3; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..91
FT                   /note="Acylphosphatase"
FT                   /id="PRO_0000158561"
FT   DOMAIN          5..91
FT                   /note="Acylphosphatase-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00520"
FT   ACT_SITE        20
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00520"
FT   ACT_SITE        38
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00520"
SQ   SEQUENCE   91 AA;  10297 MW;  6C277AE5C4C43838 CRC64;
     MKRVRAHLRI YGRVQGVGFR WSMSREARKL GVHGWVRNLP DGTVEAVIEG DPERVEALIG
     WAHQGPPLAR VTRVEVKWEE PEGLEGFKVV G