位置:首页 > 蛋白库 > DER_MYCCT
DER_MYCCT
ID   DER_MYCCT               Reviewed;         435 AA.
AC   Q2SRR7;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=GTPase Der {ECO:0000255|HAMAP-Rule:MF_00195};
DE   AltName: Full=GTP-binding protein EngA {ECO:0000255|HAMAP-Rule:MF_00195};
GN   Name=der {ECO:0000255|HAMAP-Rule:MF_00195}; Synonyms=engA;
GN   OrderedLocusNames=MCAP_0577;
OS   Mycoplasma capricolum subsp. capricolum (strain California kid / ATCC 27343
OS   / NCTC 10154).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=340047;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=California kid / ATCC 27343 / NCTC 10154;
RA   Glass J.I., Lartigue C., Pfannkoch C., Baden-Tillson H., Smith H.O.,
RA   Venter J.C., Roske K., Wise K.S., Calcutt M.J., Nelson W.C., Nierman W.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: GTPase that plays an essential role in the late steps of
CC       ribosome biogenesis. {ECO:0000255|HAMAP-Rule:MF_00195}.
CC   -!- SUBUNIT: Associates with the 50S ribosomal subunit. {ECO:0000255|HAMAP-
CC       Rule:MF_00195}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. EngA (Der) GTPase family. {ECO:0000255|HAMAP-
CC       Rule:MF_00195}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000123; ABC01662.1; -; Genomic_DNA.
DR   RefSeq; WP_011387442.1; NC_007633.1.
DR   AlphaFoldDB; Q2SRR7; -.
DR   SMR; Q2SRR7; -.
DR   EnsemblBacteria; ABC01662; ABC01662; MCAP_0577.
DR   GeneID; 23778467; -.
DR   KEGG; mcp:MCAP_0577; -.
DR   HOGENOM; CLU_016077_6_2_14; -.
DR   OMA; KFRFLEY; -.
DR   OrthoDB; 263682at2; -.
DR   PhylomeDB; Q2SRR7; -.
DR   Proteomes; UP000001928; Chromosome.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.300.20; -; 1.
DR   Gene3D; 3.40.50.300; -; 2.
DR   HAMAP; MF_00195; GTPase_Der; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR031166; G_ENGA.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR016484; GTP-bd_EngA.
DR   InterPro; IPR032859; KH_dom-like.
DR   InterPro; IPR015946; KH_dom-like_a/b.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   Pfam; PF14714; KH_dom-like; 1.
DR   Pfam; PF01926; MMR_HSR1; 2.
DR   PIRSF; PIRSF006485; GTP-binding_EngA; 1.
DR   PRINTS; PR00326; GTP1OBG.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   TIGRFAMs; TIGR03594; GTPase_EngA; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 2.
DR   PROSITE; PS51712; G_ENGA; 2.
PE   3: Inferred from homology;
KW   GTP-binding; Nucleotide-binding; Repeat; Ribosome biogenesis.
FT   CHAIN           1..435
FT                   /note="GTPase Der"
FT                   /id="PRO_1000011669"
FT   DOMAIN          4..167
FT                   /note="EngA-type G 1"
FT   DOMAIN          175..350
FT                   /note="EngA-type G 2"
FT   DOMAIN          351..435
FT                   /note="KH-like"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00195"
FT   BINDING         10..17
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00195"
FT   BINDING         57..61
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00195"
FT   BINDING         119..122
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00195"
FT   BINDING         181..188
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00195"
FT   BINDING         228..232
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00195"
FT   BINDING         293..296
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00195"
SQ   SEQUENCE   435 AA;  49776 MW;  EF414AA895ABDAF4 CRC64;
     MKKKIVAIVG KPNVGKSSLF NRIIKEKKSI VDNKPGVTRD RIYSNAEWLT REFILIDTGG
     ISVDQQLFSN EIQIQTQIAI EQADVIIFVV DFLNRLDKDD KIIAKILHKS KKPVILAINK
     YDKKTIDEHN YEFMNLGFSD LYFISSTHGI GIGDLLDKVI SYISKNDVEL KDDSTKIAII
     GKPNVGKSSL VNSLVNENRM IVSEIEGTTL DAVDISFSYN KKKYIVIDTA GIRKKSKLGQ
     TVEKYSYLRS LSAIANSDIV LLMIDATKPI TDQDTNIGGL IYDEKKPVII VVNKWDLIKN
     KQEQILKKEE EIRAYFKYLS YAKIIFISAL DKTRVTKILD LIDEIKQSLS VKVKTYVLNE
     VLNKAQLINP APEFNGNRLK IYYASQVQAY IPTFVLFCNN PNYLHFSYKR FLENQIRFSF
     GFDSIPINLI FRERK
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024