ID   DEWA_EMENI              Reviewed;         135 AA.
AC   P52750; C8V5M7; Q5AUM4;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Spore-wall fungal hydrophobin dewA;
DE   Flags: Precursor;
GN   Name=dewA; ORFNames=AN8006;
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS   M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Nidulantes.
OX   NCBI_TaxID=227321;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=7651135; DOI=10.1111/j.1365-2958.1995.tb02389.x;
RA   Stringer M.A., Timberlake W.E.;
RT   "dewA encodes a fungal hydrophobin component of the Aspergillus spore
RT   wall.";
RL   Mol. Microbiol. 16:33-44(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA   Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA   Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA   Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA   Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA   Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA   Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA   Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA   Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA   Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA   Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA   Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA   Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA   Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA   van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA   Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA   Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA   Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA   Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA   Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA   van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA   Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA   Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT   effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall. Spore wall.
CC   -!- DEVELOPMENTAL STAGE: Accumulates preferentially during asexual
CC       sporulation.
CC   -!- SIMILARITY: Belongs to the fungal hydrophobin family. {ECO:0000305}.
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DR   EMBL; U07935; AAC13762.1; -; Genomic_DNA.
DR   EMBL; AACD01000138; EAA58809.1; -; Genomic_DNA.
DR   EMBL; BN001302; CBF73692.1; -; Genomic_DNA.
DR   PIR; S67924; S67924.
DR   RefSeq; XP_681275.1; XM_676183.1.
DR   PDB; 2LSH; NMR; -; A=19-135.
DR   PDBsum; 2LSH; -.
DR   AlphaFoldDB; P52750; -.
DR   BMRB; P52750; -.
DR   SMR; P52750; -.
DR   STRING; 162425.CADANIAP00004026; -.
DR   EnsemblFungi; CBF73692; CBF73692; ANIA_08006.
DR   EnsemblFungi; EAA58809; EAA58809; AN8006.2.
DR   GeneID; 2869124; -.
DR   KEGG; ani:AN8006.2; -.
DR   VEuPathDB; FungiDB:AN8006; -.
DR   HOGENOM; CLU_2073980_0_0_1; -.
DR   InParanoid; P52750; -.
DR   OMA; CENVIAC; -.
DR   OrthoDB; 1552304at2759; -.
DR   Proteomes; UP000000560; Chromosome II.
DR   Proteomes; UP000005890; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0009277; C:fungal-type cell wall; IEA:InterPro.
DR   GO; GO:0031160; C:spore wall; IDA:AspGD.
DR   GO; GO:0005199; F:structural constituent of cell wall; IEA:InterPro.
DR   GO; GO:0042243; P:asexual spore wall assembly; IMP:AspGD.
DR   InterPro; IPR001338; Hydrophobin.
DR   InterPro; IPR019778; Hydrophobin_CS.
DR   Pfam; PF01185; Hydrophobin; 1.
DR   SMART; SM00075; HYDRO; 1.
DR   PROSITE; PS00956; HYDROPHOBIN; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cell wall; Cell wall biogenesis/degradation; Disulfide bond;
KW   Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..135
FT                   /note="Spore-wall fungal hydrophobin dewA"
FT                   /id="PRO_0000013507"
FT   CARBOHYD        60
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        44..114
FT                   /evidence="ECO:0000250"
FT   DISULFID        51..108
FT                   /evidence="ECO:0000250"
FT   DISULFID        52..84
FT                   /evidence="ECO:0000250"
FT   DISULFID        115..122
FT                   /evidence="ECO:0000250"
FT   HELIX           34..41
FT                   /evidence="ECO:0007829|PDB:2LSH"
FT   HELIX           46..48
FT                   /evidence="ECO:0007829|PDB:2LSH"
FT   STRAND          49..52
FT                   /evidence="ECO:0007829|PDB:2LSH"
FT   HELIX           55..58
FT                   /evidence="ECO:0007829|PDB:2LSH"
FT   HELIX           64..67
FT                   /evidence="ECO:0007829|PDB:2LSH"
FT   STRAND          79..81
FT                   /evidence="ECO:0007829|PDB:2LSH"
FT   STRAND          84..86
FT                   /evidence="ECO:0007829|PDB:2LSH"
FT   HELIX           87..90
FT                   /evidence="ECO:0007829|PDB:2LSH"
FT   TURN            91..93
FT                   /evidence="ECO:0007829|PDB:2LSH"
FT   TURN            96..98
FT                   /evidence="ECO:0007829|PDB:2LSH"
FT   STRAND          99..102
FT                   /evidence="ECO:0007829|PDB:2LSH"
FT   STRAND          105..114
FT                   /evidence="ECO:0007829|PDB:2LSH"
FT   STRAND          117..120
FT                   /evidence="ECO:0007829|PDB:2LSH"
FT   STRAND          122..125
FT                   /evidence="ECO:0007829|PDB:2LSH"
FT   STRAND          127..129
FT                   /evidence="ECO:0007829|PDB:2LSH"
SQ   SEQUENCE   135 AA;  13201 MW;  F3B364748293A205 CRC64;
     MRFIVSLLAF TAAATATALP ASAAKNAKLA TSAAFAKQAE GTTCNVGSIA CCNSPAETNN
     DSLLSGLLGA GLLNGLSGNT GSACAKASLI DQLGLLALVD HTEEGPVCKN IVACCPEGTT
     NCVAVDNAGA GTKAE