DEXI_MOUSE
ID DEXI_MOUSE Reviewed; 95 AA.
AC Q9WUQ7;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 14-AUG-2001, sequence version 2.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Dexamethasone-induced protein;
DE AltName: Full=Protein MYLE;
GN Name=Dexi; Synonyms=Myle;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Lung;
RX PubMed=11472984; DOI=10.1165/ajrcmb.25.1.4417;
RA Edgar A.J., Birks E.J., Yacoub M.H., Polak J.M.;
RT "Cloning of dexamethasone-induced transcript: a novel glucocorticoid-
RT induced gene that is upregulated in emphysema.";
RL Am. J. Respir. Cell Mol. Biol. 25:119-124(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Medulla oblongata, and Pancreas;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Salivary gland;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the DEXI family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF152470; AAD34163.2; -; mRNA.
DR EMBL; AK007644; BAB25159.2; -; mRNA.
DR EMBL; AK032104; BAC27703.1; -; mRNA.
DR EMBL; BC017551; AAH17551.1; -; mRNA.
DR CCDS; CCDS37252.1; -.
DR RefSeq; NP_067403.2; NM_021428.4.
DR RefSeq; XP_011244293.1; XM_011245991.1.
DR RefSeq; XP_017172595.1; XM_017317106.1.
DR RefSeq; XP_017172596.1; XM_017317107.1.
DR AlphaFoldDB; Q9WUQ7; -.
DR STRING; 10090.ENSMUSP00000047676; -.
DR PaxDb; Q9WUQ7; -.
DR PRIDE; Q9WUQ7; -.
DR Antibodypedia; 11474; 122 antibodies from 21 providers.
DR DNASU; 58239; -.
DR Ensembl; ENSMUST00000038281; ENSMUSP00000047676; ENSMUSG00000038055.
DR Ensembl; ENSMUST00000184863; ENSMUSP00000139108; ENSMUSG00000038055.
DR GeneID; 58239; -.
DR KEGG; mmu:58239; -.
DR UCSC; uc007ydx.1; mouse.
DR CTD; 28955; -.
DR MGI; MGI:1926236; Dexi.
DR VEuPathDB; HostDB:ENSMUSG00000038055; -.
DR eggNOG; ENOG502S66C; Eukaryota.
DR GeneTree; ENSGT00390000013271; -.
DR HOGENOM; CLU_184633_0_0_1; -.
DR InParanoid; Q9WUQ7; -.
DR OMA; PIYAQLD; -.
DR OrthoDB; 1552026at2759; -.
DR PhylomeDB; Q9WUQ7; -.
DR TreeFam; TF338557; -.
DR BioGRID-ORCS; 58239; 1 hit in 73 CRISPR screens.
DR ChiTaRS; Dexi; mouse.
DR PRO; PR:Q9WUQ7; -.
DR Proteomes; UP000000589; Chromosome 16.
DR RNAct; Q9WUQ7; protein.
DR Bgee; ENSMUSG00000038055; Expressed in pontine nuclear group and 237 other tissues.
DR Genevisible; Q9WUQ7; MM.
DR InterPro; IPR023259; Dexamethasone-induced.
DR PANTHER; PTHR17070; PTHR17070; 1.
DR Pfam; PF15198; Dexa_ind; 1.
DR PRINTS; PR02032; DEXMETHSNEIP.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..95
FT /note="Dexamethasone-induced protein"
FT /id="PRO_0000096670"
SQ SEQUENCE 95 AA; 10402 MW; 4F293AD7F2326B14 CRC64;
MPGARVAAHL DALGPLVSYV QPPLLPSMFY VGLFFVNVLI LYYAFLMEYI VLNVGLVFLP
EDLDQALVDL GVLSDPGSGL YDADSELDVF DGYLE