ID   DEXT_ARTGO              Reviewed;         640 AA.
AC   P70744;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Dextranase;
DE            EC=3.2.1.11;
DE   AltName: Full=Alpha-1,6-glucan-6-glucanohydrolase;
DE   AltName: Full=Endodextranase;
DE   Flags: Precursor;
OS   Arthrobacter globiformis.
OC   Bacteria; Actinobacteria; Micrococcales; Micrococcaceae; Arthrobacter.
OX   NCBI_TaxID=1665;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=T-3044;
RA   Oguma T., Kurokawa T., Tobe K., Kitao S., Kobayashi M.;
RL   Submitted (NOV-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endohydrolysis of (1->6)-alpha-D-glucosidic linkages in
CC         dextran.; EC=3.2.1.11;
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 49 family. {ECO:0000305}.
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DR   EMBL; D88361; BAA13596.1; -; Genomic_DNA.
DR   AlphaFoldDB; P70744; -.
DR   SMR; P70744; -.
DR   CAZy; GH49; Glycoside Hydrolase Family 49.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0033904; F:dextranase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 2.160.20.10; -; 1.
DR   Gene3D; 2.60.350.10; -; 1.
DR   InterPro; IPR041402; B_solenoid_dext.
DR   InterPro; IPR035953; Dextranase_N-ter.
DR   InterPro; IPR005192; Glyco_hydro_49_C.
DR   InterPro; IPR023226; Glyco_hydro_49_N_dom.
DR   InterPro; IPR041274; IPU_b_solenoid.
DR   InterPro; IPR012334; Pectin_lyas_fold.
DR   InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR   Pfam; PF18841; B_solenoid_dext; 1.
DR   Pfam; PF03718; Glyco_hydro_49; 1.
DR   Pfam; PF17433; Glyco_hydro_49N; 1.
DR   Pfam; PF18783; IPU_b_solenoid; 1.
DR   SUPFAM; SSF101596; SSF101596; 1.
DR   SUPFAM; SSF51126; SSF51126; 1.
PE   3: Inferred from homology;
KW   Glycosidase; Hydrolase; Secreted; Signal.
FT   SIGNAL          1..32
FT                   /evidence="ECO:0000255"
FT   CHAIN           33..640
FT                   /note="Dextranase"
FT                   /id="PRO_0000012210"
SQ   SEQUENCE   640 AA;  71143 MW;  4AC7864A96A537D2 CRC64;
     MPGTGLGRLA KHVTAAAAVF LISTGAVLPA QAETAPGSTP SAAPAASVEK HPITTANNGN
     LHTWWHDNGV FSPAAPTQSD EVRRSSLYDV RVAQANQPQK AYDAFTYMSI PRSGKGKIGY
     TEEDGAEFSS EAGLTMSWSS FEYAKDVWVE VSLRTGQTIS SADQVQIRPS SYNFEKQLVD
     ADTVRIKVPY SDAGYRFSVE FEPQLYTAYN DMSGDSGKLT TEAEGNRPIH TEPRNSMMVF
     AEPKLRGEQK ERLVPTQESG SIHYPEPGEV RNLNSVSAEI IYFRPGTYSM GSDYHAVLPA
     NVKWVYLAPG AYVKGAFRFL HDTQSQYKVT GYGVLSGEQY VYEADTNNSY NHLSGASNCH
     SSCVKMLQFA SADAEQKLDL QGVTVAEPPY HSFVVYGNEQ TFHMNVENYK QVGSWYWQTD
     GIELYQGSTM KNTFFNANDD VLKMYHSDVS IDNTVVWKNE NGPVVQWGWT PRNIDNVNVT
     NTTVIHNRMY WKDVKYNTCI FNSSSHWEDM GSTTKADPNT TVKNMRFENT TVEGMTNCAI
     RVYALSDTEN IHIKNFNIGS WNGLDWTSQV SHLKRYTNSA GEKVTIGNEL PDGNGLAIEN
     YSVGGQVIEK SGGNWSDYQL GRLGFDGENW DSWNAWKSAP