DF117_ARATH
ID DF117_ARATH Reviewed; 79 AA.
AC Q2V4G3;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-JAN-2006, sequence version 1.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=Defensin-like protein 117;
DE Flags: Precursor;
GN OrderedLocusNames=At1g58055; ORFNames=T15M6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17565583; DOI=10.1111/j.1365-313x.2007.03136.x;
RA Silverstein K.A.T., Moskal W.A. Jr., Wu H.C., Underwood B.A., Graham M.A.,
RA Town C.D., VandenBosch K.A.;
RT "Small cysteine-rich peptides resembling antimicrobial peptides have been
RT under-predicted in plants.";
RL Plant J. 51:262-280(2007).
RN [5]
RP GENE FAMILY.
RX PubMed=15955924; DOI=10.1104/pp.105.060079;
RA Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL Plant Physiol. 138:600-610(2005).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
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DR EMBL; AC079604; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002684; AEE33492.1; -; Genomic_DNA.
DR EMBL; DQ912209; ABI34017.1; -; mRNA.
DR EMBL; EF182797; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_001031204.1; NM_001036127.3.
DR AlphaFoldDB; Q2V4G3; -.
DR STRING; 3702.AT1G58055.1; -.
DR PaxDb; Q2V4G3; -.
DR ProteomicsDB; 224256; -.
DR EnsemblPlants; AT1G58055.1; AT1G58055.1; AT1G58055.
DR GeneID; 3767564; -.
DR Gramene; AT1G58055.1; AT1G58055.1; AT1G58055.
DR KEGG; ath:AT1G58055; -.
DR Araport; AT1G58055; -.
DR TAIR; locus:1009023096; AT1G58055.
DR HOGENOM; CLU_183259_1_0_1; -.
DR OMA; CESGICC; -.
DR OrthoDB; 1823398at2759; -.
DR PhylomeDB; Q2V4G3; -.
DR PRO; PR:Q2V4G3; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q2V4G3; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..79
FT /note="Defensin-like protein 117"
FT /id="PRO_0000379679"
FT DISULFID 40..75
FT /evidence="ECO:0000250"
FT DISULFID 46..68
FT /evidence="ECO:0000250"
FT DISULFID 53..73
FT /evidence="ECO:0000250"
FT DISULFID 57..74
FT /evidence="ECO:0000250"
SQ SEQUENCE 79 AA; 8450 MW; DAB4FBED745DEC76 CRC64;
MTTTKTMLVA FVLTLFFVIS SVHCSDGTSG YGITEATKRC FTPAPCTRGL FYCQTFCSSL
SAVLIGVCES GICCCILNQ