ID   DF172_ARATH             Reviewed;          84 AA.
AC   P82774;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   29-MAR-2004, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Defensin-like protein 172;
DE   AltName: Full=Low-molecular-weight cysteine-rich protein 60;
DE            Short=Protein LCR60;
DE   Flags: Precursor;
GN   Name=LCR60; OrderedLocusNames=At2g20208; ORFNames=F11A3;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000305};
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia {ECO:0000269|PubMed:10617197};
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3] {ECO:0000305}
RP   IDENTIFICATION.
RX   PubMed=11437247; DOI=10.1023/a:1010664704926;
RA   Vanoosthuyse V., Miege C., Dumas C., Cock J.M.;
RT   "Two large Arabidopsis thaliana gene families are homologous to the
RT   Brassica gene superfamily that encodes pollen coat proteins and the male
RT   component of the self-incompatibility response.";
RL   Plant Mol. Biol. 46:17-34(2001).
RN   [4]
RP   GENE FAMILY.
RX   PubMed=15955924; DOI=10.1104/pp.105.060079;
RA   Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT   "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL   Plant Physiol. 138:600-610(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
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DR   EMBL; AC006569; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002685; AEC06981.1; -; Genomic_DNA.
DR   RefSeq; NP_001031377.1; NM_001036300.2.
DR   AlphaFoldDB; P82774; -.
DR   SMR; P82774; -.
DR   BioGRID; 528285; 1.
DR   PaxDb; P82774; -.
DR   PRIDE; P82774; -.
DR   EnsemblPlants; AT2G20208.1; AT2G20208.1; AT2G20208.
DR   GeneID; 3767924; -.
DR   Gramene; AT2G20208.1; AT2G20208.1; AT2G20208.
DR   KEGG; ath:AT2G20208; -.
DR   Araport; AT2G20208; -.
DR   TAIR; locus:1009023195; AT2G20208.
DR   HOGENOM; CLU_196273_0_0_1; -.
DR   InParanoid; P82774; -.
DR   OMA; QNMGCTA; -.
DR   OrthoDB; 1597752at2759; -.
DR   PhylomeDB; P82774; -.
DR   PRO; PR:P82774; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; P82774; baseline and differential.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   InterPro; IPR039641; LCR.
DR   PANTHER; PTHR36788; PTHR36788; 1.
PE   2: Evidence at transcript level;
KW   Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..84
FT                   /note="Defensin-like protein 172"
FT                   /id="PRO_0000017298"
FT   DISULFID        27..74
FT                   /evidence="ECO:0000250"
FT   DISULFID        34..56
FT                   /evidence="ECO:0000250"
FT   DISULFID        40..68
FT                   /evidence="ECO:0000250"
FT   DISULFID        44..70
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   84 AA;  8914 MW;  2146CD48C5D230CB CRC64;
     MAKASSTLVL SIIFLVMFAL VEQNMGCTAT MGPCEKDKSC SATCRATFGD RANGFCDYST
     STSPGGECTC VYHCPPVVPH ESHL