ID   DF180_ARATH             Reviewed;         127 AA.
AC   P82772;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Putative defensin-like protein 180;
DE   AltName: Full=Putative low-molecular-weight cysteine-rich protein 58;
DE            Short=Protein LCR58;
DE   Flags: Precursor;
GN   Name=LCR58; OrderedLocusNames=At5g38317; ORFNames=MSI17;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000305};
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9679202; DOI=10.1093/dnares/5.2.131;
RA   Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence
RT   features of the regions of 1,381,565 bp covered by twenty one physically
RT   assigned P1 and TAC clones.";
RL   DNA Res. 5:131-145(1998).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3] {ECO:0000305}
RP   IDENTIFICATION.
RX   PubMed=11437247; DOI=10.1023/a:1010664704926;
RA   Vanoosthuyse V., Miege C., Dumas C., Cock J.M.;
RT   "Two large Arabidopsis thaliana gene families are homologous to the
RT   Brassica gene superfamily that encodes pollen coat proteins and the male
RT   component of the self-incompatibility response.";
RL   Plant Mol. Biol. 46:17-34(2001).
RN   [4]
RP   GENE FAMILY.
RX   PubMed=15955924; DOI=10.1104/pp.105.060079;
RA   Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT   "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL   Plant Physiol. 138:600-610(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC   -!- CAUTION: Contains 8 disulfide bonds instead of the 4 disulfide bonds,
CC       which are conserved features of the family. {ECO:0000305}.
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DR   EMBL; AB011481; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002688; AED94295.1; -; Genomic_DNA.
DR   RefSeq; NP_001031979.1; NM_001036902.1.
DR   AlphaFoldDB; P82772; -.
DR   STRING; 3702.AT5G38317.1; -.
DR   PaxDb; P82772; -.
DR   PRIDE; P82772; -.
DR   EnsemblPlants; AT5G38317.1; AT5G38317.1; AT5G38317.
DR   GeneID; 3771358; -.
DR   Gramene; AT5G38317.1; AT5G38317.1; AT5G38317.
DR   KEGG; ath:AT5G38317; -.
DR   Araport; AT5G38317; -.
DR   TAIR; locus:1009023434; AT5G38317.
DR   eggNOG; ENOG502SD1Z; Eukaryota.
DR   HOGENOM; CLU_158287_1_1_1; -.
DR   InParanoid; P82772; -.
DR   OMA; CETCDER; -.
DR   OrthoDB; 1411313at2759; -.
DR   PhylomeDB; P82772; -.
DR   PRO; PR:P82772; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   InterPro; IPR039641; LCR.
DR   PANTHER; PTHR36788; PTHR36788; 1.
PE   3: Inferred from homology;
KW   Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..127
FT                   /note="Putative defensin-like protein 180"
FT                   /id="PRO_0000017296"
FT   DISULFID        29..70
FT                   /evidence="ECO:0000250"
FT   DISULFID        36..55
FT                   /evidence="ECO:0000250"
FT   DISULFID        39..64
FT                   /evidence="ECO:0000250"
FT   DISULFID        43..66
FT                   /evidence="ECO:0000250"
FT   DISULFID        81..127
FT                   /evidence="ECO:0000250"
FT   DISULFID        92..112
FT                   /evidence="ECO:0000250"
FT   DISULFID        97..121
FT                   /evidence="ECO:0000250"
FT   DISULFID        101..123
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   127 AA;  13625 MW;  50E4B646530A52D8 CRC64;
     MERITSLVFF ASFLIIFVSG VNQTRADSCD ESLGLCETCD ERCQAKHGPS CISKCDGEVG
     MLSCTCTYEC GPPLPPKGNV CSGGTGMCSG KCPYKCCDTS CAQKYNGGRG FCNSFGNYNF
     CQCEYPC